I have a stable system as to fonts with Suitcase Fusion and Office 2008 (and CS3). Office '08 apps seem to launch faster as well.
I wanted to use the newest fonts, but retain old favorites if newer versions weren't available. So I moved fonts out of /Library/Fonts/ and imported into three Suitcase font sets, Adobe, Microsoft and Library, storing all fonts in Suitcase vault.
Then I eliminated duplicates, choosing OpenType over TrueType and keeping the newest versions.
So far, so good.
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